Alli

Are Alli’s Side Effects Worth It?

Also known as the leakage and staining embarassment producing diet pill, due to is loose stool side effects, Alli is the reduced-strength version of the “fat blocker” Orlistat (Xenical), a prescription drug developed by GlaxoSmithKline to treat obesity. It is FDA approved for non-prescription sale to overweight adults. Alli is designed to be used in conjunction with a low-calorie, low-fat diet and regular exercise. So-called fat blocking products have been available for years.

How does Alli work?
Alli promotes weight loss by inhibiting the absorption of fat by the intestines, effectively reducing calorie intake into the body. The enzyme Lipase helps break down dietary fat to provide energy, or to be stored in the body for future use. Alli works by deactivating Lipase. The increased levels of undigested fat move through the intestines and are eliminated through the bowel. Due to Alli’s mechanism of action, it is recommended that no more than 15 grams of fat are consumed in each meal. Eating higher amounts of fat can cause unwanted side effects.

How much weight could be lost using Alli?
Alli has been shown to promote weight loss, but the weight loss may only be a few pounds more than would be dropped through diet and exercise alone. Only a small number of studies have evaluated Alli. The majority of studies have been carried out on the stronger prescription-strength version of the drug, Xenical.  However, even, the average weight loss reported for Xenical is relatively modest, at about 6 pounds more than could be achieved by diet and exercise alone, after one year. So at half the strength of Xenical, taking Alli could potentially result in an average weight reduction of 3 pounds in a 1 year period. This is in addition to around 8 pounds lost through diet and exercise alone over that time.

What are the side effects of using Alli? Side effects can include:
• Gas with an oily anal discharge
• Loose stools or diarrhea
• Frequent bowel movements
• Difficult-to-control bowel movements

These bowel problems are caused by increased levels of undigested fat passing through the digestive system.

When not to take Alli?  Do not take Alli if you are:
• At a healthy weight
• Taking cyclosporine
• The recipient of an organ transplant
• Experiencing problems digesting food

If you have a chronic digestive disease, such as Inflammatory Bowel Disease (Crohn’s or Colitis) or Irritable Bowel Syndrome (IBS), where diarrhea is a problem, Alli should not be taken, since the drug would probably intensify the diarrhea. For slimmers with IBS, however, where constipation is the main symptom, Alli could help. The weight loss drug could also pose risks for dieters taking blood-thinning medication or suffering from diabetes or thyroid disease.

Orlistat has been shown to reduce the absorption of certain fat-soluble vitamins, such as vitamins A, D and E. If using Alli, it is advisable to take daily vitamin supplements to prevent potential nutrient deficiencies.

How long to take Alli for?
According to the manufacturer, most weight loss takes place within the first 6 months. Many dieters who take diet pills to lose weight regain the weight they lost when they stop taking the pills. As a general rule, however, to keep the weight off, some dieters ignore the directions for use and continue taking the pills indefinitely.

Common misspellings: Alle, AlliDiet, AlliPill, Alli Deit Pill, Allu, alli.com, Ally

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